Hiv-1 Gp41 Ectodomain Induces Activation of the Cd74-mediated Erk/mapk Pathway to Enhance Viral Infection
نویسندگان
چکیده
PATHWAY TO ENHANCE VIRAL INFECTION Chang Zhou, Lu Lu , Suiyi Tan, Shibo Jiang , Ying-Hua Chen Laboratory of Immunology, School of Life Sciences; Beijing Key Laboratory for Protein Therapeutics; Protein Science Laboratory of MOE, Tsinghua University Beijing 100084, China; MOE/MOH Key Laboratory of Medical Molecular Virology, Institute of Medical Microbiology, Shanghai Medical College, Fudan University, Shanghai 200032, China; Laboratory of Viral Immunology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA
منابع مشابه
Antibody neutralization escape mediated by point mutations in the intracytoplasmic tail of human immunodeficiency virus type 1 gp41.
The persistence of human immunodeficiency virus type 1 (HIV-1) infection in the presence of robust host immunity has been associated in part with variation in viral envelope proteins leading to antigenic variation and escape from neutralizing antibodies. Previous studies of natural neutralization escape mutants have predominantly focused on gp120 and gp41 ectodomain sequence variations that alt...
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